Полина Степенски

Должность: Трансплантолог, заведующая отделением ТКМ
Языки: Русский, Иврит, Английский
Принимает: детей и взрослых

Профессор Полина Степенски (Стефански) – руководитель отделения трансплантации костного мозга университетской клиники “Хадасса” в Иерусалиме.

Образование

  • 1991-1994 – Cherill Spenser Nursing School, школа медсестер, Хайфа, Израиль
  • 1994-1998 – Медицинский факультет Еврейского университета, Иерусалим
  • 1999 – Получение степени доктора медицинских наук
  • 1998-2003 – Ординатура при отделении педиатрии
  • 2003-2006 – Специализация в области детской онкогематологии

Научные публикации

Inborn errors of immunity reveal the molecular requirements for the generation and maintenance of human IL-9 expressing cells
Prognostic Factors Associated With Increased Mortality in Pediatric Veno-Occlusive Disease Following Hematopoietic Cell Transplantation
Endothelial Activation and Stress Index Score as a Prognostic Factor of Cytokine Release Syndrome in CAR-T Patients - A Retrospective Analysis of Multiple Myeloma and Large B-Cell Lymphoma Cohorts
Successful Haematopoietic Stem Cell Transplantation for LRBA Deficiency with Fludarabine, Treosulfan, and Thiotepa-Based Conditioning
Genotype-phenotype correlations in chronic granulomatous disease: insights from a large national cohort
Clinical evaluation and determinants of response to HBI0101 (BCMA CART) therapy in relapsed/refractory multiple myeloma
Outcomes of allogeneic haematopoietic cell transplantation for myelofibrosis in children and adolescents: the retrospective study of the EBMT Paediatric Diseases WP
Wiskott-Aldrich syndrome: a study of 577 patients defines the genotype as a biomarker for disease severity and survival
Development and Validation of a Prediction Model of Outcome After B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T-Cell Therapy in Relapsed/Refractory Multiple Myeloma
Long-term and real-world safety and efficacy of retroviral gene therapy for adenosine deaminase deficiency
Management of Atopy with Dupilumab and Omalizumab in CADINS Disease
Combined Immunodeficiency Caused by a Novel Nonsense Mutation in LCK
Chronic graft-versus-host disease detected by tissue-specific cell-free DNA methylation biomarkers
Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Apoptosis, TNF Alpha and Interferon Gamma Response Gene mRNA Expression in T Lymphocytes
Tumor-infiltrating lymphocyte transfusion in a patient with treatment refractory triple negative breast cancer
Sclerotic-Type Cutaneous Chronic Graft-Versus-Host Disease Exhibits Activation of T Helper 1 and OX40 Cytokines
High rate of adenovirus detection in gastrointestinal biopsies of symptomatic stem cell transplant recipients
Clonal Myeloid Dysplasia Following CAR T-Cell Therapy: Chicken or the Egg?
Risk and promise: an 11-year, single-center retrospective study of severe acute GVHD in pediatric patients undergoing allogeneic HSCT for nonmalignant diseases
Long-Term Results with Thiotepa-Containing Conditioning Regimens for Autologous Stem Cell Transplantation
Defibrotide plus best standard of care compared with best standard of care alone for the prevention of sinusoidal obstruction syndrome (HARMONY): a randomised, multicentre, phase 3 trial
Response rates of extra-nodal diffuse large B cell lymphoma to anti-CD19-CAR T cells: A real word retrospective multicenter study
Outcome of haematopoietic cell transplantation in children with lysosomal acid lipase deficiency: a study on behalf of the EBMT Inborn Errors Working Party
SURVIVAL OF PEDIATRIC PATIENTS WITH NON-MALIGNANT DISEASES REQUIRING HOSPITALIZATION IN THE INTENSIVE CARE UNIT FOLLOWING HEMATOPOIETIC STEM CELL TRANSPLANTATION AND RISK FACTORS FOR MORTALITY
STEM CELL TRANSPLANTATIONS FOR PATIENTS WITH FANCONI ANEMIA: AN ISRAELI TERTIARY CENTER EXPERIENCE
Neurological complications following pediatric allogeneic hematopoietic stem cell transplantation: Risk factors and outcome
SLP76 Mutation Associated with Combined Immunodeficiency and EBV-Related Lymphoma
Vedolizumab for pediatric patients with gastrointestinal acute graft-versus-host-disease
Incremental donor lymphocyte infusion to treat mixed chimerism after allogeneic stem cell transplantation in children with non-malignant diseases
Two decades of stem cell transplantation in patients with Fanconi anemia: Analysis of factors affecting transplant outcomes
Development and manufacture of novel locally produced anti-BCMA CAR T cells for the treatment of relapsed/refractory multiple myeloma: results from a phase I clinical trial
Feasibility of a Novel Academic BCMA-CART (HBI0101) for the Treatment of Relapsed and Refractory AL Amyloidosis
Clinically Complex LRBA Deficiency Due to a Founder Allele in the Georgian Jewish Population
Ibrutinib Treatment of Pediatric Chronic Graft-versus-Host Disease: Primary Results from the Phase 1/2 iMAGINE Study
Clinical and immunophenotypic characteristics of familial leukemia predisposition caused by PAX5 germline variants
Autoimmune Cytopenias Post Hematopoietic Stem Cell Transplantation in Pediatric Patients With Osteopetrosis and Other Nonmalignant Diseases
GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans
Correction to: Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients
Lessons Learned From Five Years of Newborn Screening for Severe Combined Immunodeficiency in Israel
Preclinical evaluation and structural optimization of anti-BCMA CAR to target multiple myeloma
Survival of pediatric patients requiring admission in the intensive care unit post hematopoietic stem cell transplantation: Prognostic factors associated with mortality
Neutrophil decline rate following autologous transplant for lymphoma is a predictor of patients' outcome
Social determinants of health and primary immunodeficiency
Clinical presentation and analysis of genotype-phenotype correlations in patients with malignant infantile osteopetrosis
The expansion of human T-bethighCD21low B cells is T cell dependent
The Clinical Aspect of Adaptor Molecules in T Cell Signaling: Lessons Learnt From Inborn Errors of Immunity
Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients
Evaluation of gastrointestinal symptoms in pediatric patients post hematopoietic stem cell transplantation: Ileo-colonoscopy versus sigmoidoscopy. A single-center experience and review of literature
Toxicity and efficacy of chimeric antigen receptor T-cell therapy in patients with diffuse large B-cell lymphoma above the age of 70 years compared to younger patients - a matched control multicenter cohort study
Characterization of a L136P mutation in Formin-like 2 (FMNL2) from a patient with chronic inflammatory bowel disease
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Профессор Полина Стефански рассказывает о себе и своей работе.
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Заболевания
Болезнь Вольмана
Идиопатическая тромбоцитопеническая пурпура
Множественная миелома
Остеопетроз
Врожденный дискератоз
Первичные иммунодефициты
Анемия Даймонда-Блекфена
Дефицит аденозиндезаминазы 2 (DADA2)
Дефицит лизосомной кислой липазы
Дефицит активируемой цитидиндезаминазы
Процедуры
Трансплантация костного мозга
Полное экзомное секвенирование "трио"
Tерапия CAR-T-клетками
Поиск донора костного мозга
Типирование генов гистосовместимости человека
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