Цви Фридлендер

Научные публикации

• Neutrophils in the tumor microenvironment - when a company becomes a crowd
• Breath of Health: spectroscopy-based breath test for the detection of SARS-CoV-2
• RNA Sequencing Reveals Unique Transcriptomic Signatures of the Thyroid in a Murine Lung Cancer Model Treated with PD-1 and PD-L1 Antibodies
• Elevated cfDNA after exercise is derived primarily from mature polymorphonuclear neutrophils, with a minor contribution of cardiomyocytes
• The DNA methylome of human vascular endothelium and its use in liquid biopsies
• How Accurate Is the Diagnosis of "Chronic Obstructive Pulmonary Disease" in Patients Hospitalized with an Acute Exacerbation?
• Targeted nanoparticles modify neutrophil function in vivo
• Recurrent haemoptysis: a rare diagnosis of kaposiform lymphangiomatosis and review of literature
• Neutrophil phenotypes and functions in cancer: A consensus statement
• Universal lung epithelium DNA methylation markers for detection of lung damage in liquid biopsies
• The Bilateral Interplay between Cancer Immunotherapies and Neutrophils' Phenotypes and Sub-Populations
• Editorial: Neutrophils in Cancer
• Residual symptoms, lung function, and imaging findings in patients recovering from SARS-CoV-2 infection
• The dual role of neutrophils in cancer
• Accelerated low-density neutrophil transition in sickle cell anaemia may contribute to disease pathophysiology
• Tumor-Derived Factors Differentially Affect the Recruitment and Plasticity of Neutrophils
• Tumor-Associated Neutrophils Drive B-cell Recruitment and Their Differentiation to Plasma Cells
• Therapeutic Success of Tiotropium/Olodaterol, Measured Using the Clinical COPD Questionnaire (CCQ), in Routine Clinical Practice: A Multinational Non-Interventional Study
• Blocking Migration of Polymorphonuclear Myeloid-Derived Suppressor Cells Inhibits Mouse Melanoma Progression
• The Effect of a Multidisciplinary Integrated Approach on Outcomes in Chronic Obstructive Pulmonary Disease
• Prophylactic use of tranexamic acid for prevention of bleeding during transbronchial lung biopsies - A randomized, double-blind, placebo-controlled trial
• NETosis in cancer: a critical analysis of the impact of cancer on neutrophil extracellular trap (NET) release in lung cancer patients vs. mice
• Circulating neutrophil subsets in advanced lung cancer patients exhibit unique immune signature and relate to prognosis
• Improvement In Self-Reported Physical Functioning With Tiotropium/Olodaterol In Central And Eastern European COPD Patients
• Increased Regeneration Following Stress-Induced Lung Injury in Bleomycin-Treated Chimeric Mice with CD44 Knockout Mesenchymal Cells
• Tumour-associated neutrophils in patients with cancer
• Neutrophil Diversity in Health and Disease
• Benralizumab for the Prevention of COPD Exacerbations
• VICKZ1 enhances tumor progression and metastasis in lung adenocarcinomas in mice
• Interactions among myeloid regulatory cells in cancer
• Microenvironmental Cues Determine Tumor Cell Susceptibility to Neutrophil Cytotoxicity
• Cancer-related circulating and tumor-associated neutrophils - subtypes, sources and function
• Myeloid Regulatory Cells: New and Exciting Players in the Immunology of Lung Cancer
• TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells
• Inhaled therapies in patients with moderate COPD in clinical practice: current thinking
• Tumor-associated neutrophils induce apoptosis of non-activated CD8 T-cells in a TNFα and NO-dependent mechanism, promoting a tumor-supportive environment
• Control of immune cell entry through the tumour vasculature: a missing link in optimising melanoma immunotherapy?
• Neutrophils as active regulators of the immune system in the tumor microenvironment
• The association between osteopontin gene polymorphisms, osteopontin expression and sarcoidosis
• Characteristics of Sarcoidosis in Patients with Previous Malignancy: Causality or Coincidence?
• Organizing pneumonia following treatment with pembrolizumab for metastatic malignant melanoma - A case report
• Tumor-associated neutrophils display a distinct N1 profile following TGFβ modulation: A transcriptomics analysis of pro- vs. antitumor TANs
• Endobrochial Ultrasound Needle Breakdown During Transbronchial Needle Aspiration
• The diversity of circulating neutrophils in cancer
• Plasticity beyond cancer cells and the "immunosuppressive switch"
• Cluster of Fusarium solani isolations in a Bronchoscopy Unit
• Recurrent Eosinophilic Pneumonia in a Patient with Isolated Immunoglobulin M Deficiency and Celiac Disease
• Promoting metastasis: neutrophils and T cells join forces
• Splenectomy inhibits non-small cell lung cancer growth by modulating anti-tumor adaptive and innate immune response
• Isolation and Characterization of Neutrophils with Anti-Tumor Properties
• Surgical cytoreduction restores the antitumor efficacy of a Listeria monocytogenes vaccine in malignant pleural mesothelioma
• Overexpression of Telomerase Protects Human and Murine Lung Epithelial Cells from Fas- and Bleomycin-Induced Apoptosis via FLIP Upregulation
• Phenotypic diversity and plasticity in circulating neutrophil subpopulations in cancer
• The Multifaceted Roles Neutrophils Play in the Tumor Microenvironment
• Neutrophils recruit regulatory T-cells into tumors via secretion of CCL17--a new mechanism of impaired antitumor immunity
• Modifying tumor-associated macrophages: An important adjunct to immunotherapy
• Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression
• Using macrophage activation to augment immunotherapy of established tumours
• Changes in the local tumor microenvironment in recurrent cancers may explain the failure of vaccines after surgery
• Randomized controlled crossover trial of a new oscillatory device as add-on therapy for COPD
• Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness
• A positive-margin resection model recreates the postsurgical tumor microenvironment and is a reliable model for adjuvant therapy evaluation
• Characterization of surgical models of postoperative tumor recurrence for preclinical adjuvant therapy assessment
• Tumor-associated neutrophils: friend or foe?
• Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils
• Treating tumors with a vaccinia virus expressing IFNβ illustrates the complex relationships between oncolytic ability and immunogenicity
• Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models
• Activation of mitogen-activated protein kinases by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) plays an important role in macrophage stimulation
• Sildenafil to facilitate weaning from inhaled nitric oxide and mechanical ventilation in a patient with severe secondary pulmonary hypertension and a patent foramen ovale
• Pharmacologic activation of the innate immune system to prevent respiratory viral infections
• Chemotherapy delivered after viral immunogene therapy augments antitumor efficacy via multiple immune-mediated mechanisms
• Association between CD14 gene polymorphisms and disease phenotype in sarcoidosis
• Monocyte chemoattractant protein-1 blockade inhibits lung cancer tumor growth by altering macrophage phenotype and activating CD8+ cells
• Exogenous lipoid pneumonia caused by paraffin in an amateur fire breather
• Activation of the nucleotide oligomerization domain signaling pathway by the non-bacterially derived xanthone drug 5'6-dimethylxanthenone-4-acetic acid (Vadimezan)
• CCL2 blockade augments cancer immunotherapy
• Expression of IFN-beta enhances both efficacy and safety of oncolytic vesicular stomatitis virus for therapy of mesothelioma
• Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN
• Evaluation of an attenuated vesicular stomatitis virus vector expressing interferon-beta for use in malignant pleural mesothelioma: heterogeneity in interferon responsiveness defines potential efficacy
• The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cells in vitro and in vivo with particular efficacy for small cell lung cancer
• Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy
• Bronchoscopy in octogenarians
• B-cell depletion using an anti-CD20 antibody augments antitumor immune responses and immunotherapy in nonhematopoetic murine tumor models
• Association between cytomegalovirus infection and venous thromboembolism
• Telomerase activity in bleomycin-induced epithelial cell apoptosis and lung fibrosis
• Late-onset sarcoidosis after liver transplantation for primary biliary cirrhosis
• Obstructing tracheal pulmonary Langerhans cell histiocytosis
• Recurrent infusion phlebitis induced by cyclosporine
• Osteomyelitis of the pubis after strenuous exercise. A case report and review of the literature
• Myocardial infarction in a patient with beta-thalassemia major: first report
• Metastatic carcinoma presenting with concomitant eosinophilia and thromboembolism
• Pleural effusion
• Resistance to adjuvant arthritis is due to protective antibodies against heat shock protein surface epitopes and the induction of IL-10 secretion
• The evaluation of pleural effusions in patients with heart failure
• Pneumomediastinum following drug abuse
• Mefloquine-induced acute hepatitis
• Monocytes confer CD14 antigenicity on activated lymphocytes
• Changes in cytokine production of breast cancer patients treated with interferons
• Multidrug resistance: its significance in hematological malignancies and its role in normal tissues and blood cells