Яков Беркун

Должность: Иммунолог, педиатр
Языки: Русский, Английский, Иврит
Принимает: детей и взрослых

Профессор Яков Беркун.

Образование

  • Проф. Яков Беркун получил степень доктора медицины в медицинской школе "Хадасса" при Еврейском университете в Иерусалим.
  • Прошел специализацию по клинической иммунологии и аллергологии, а также интернатуру в университетской клинике "Хадасса"
  • Закончил резидентуру по педиатрии в больнице Бикур Холим, при медицинской школе "Хадасса".

Специализация

Специализируется в области клинической иммунологии и аллергологии и лечении следующих заболеваний:

  • Ювенильный артрит
  • Системные заболеваний у детей
  • Хроническая лихорадка
  • Пищевые и лекарственные аллергии

Профессиональная деятельность

Заведующий отделением педиатрии в "Хадассе" на горе Скопус.
Лектор медицинского факультета в Тель-Авивском университете.

Научные публикации

Successful Haematopoietic Stem Cell Transplantation for LRBA Deficiency with Fludarabine, Treosulfan, and Thiotepa-Based Conditioning
Development of the 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria, Phase III-D Report: Multicriteria Decision Analysis
Disease flares with baricitinib dose reductions and development of flare criteria in patients with CANDLE/PRAAS
2023 ACR/EULAR antiphospholipid syndrome classification criteria
The 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria
Tofacitinib-induced progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome
Platelet count and risk of severe illness in hospitalised children with Influenza-Like illness
Evaluation and Management of Deficiency of Adenosine Deaminase 2: An International Consensus Statement
Pediatric respiratory admissions and related viral infections during the COVID-19 pandemic
Bullous Hemorrhagic Target Lesions in IgA Leukocytoclastic Vasculitis
Risk factors for haemodynamic compromise in multisystem inflammatory syndrome in children: a multicentre retrospective study
Multisystem inflammatory syndrome in children associated with COVID-19 presenting as cervical inflammation
Obstacles in Early Diagnosis of Children With Juvenile Idiopathic Arthritis: A Nationwide Israeli Retrospective Study
Case Series of Myocarditis Following mRNA COVID Vaccine Compared to Pediatric Multisystem Inflammatory Syndrome: Multicenter Retrospective Study
Sechs Fälle von Pityriasis rosea nach SARS-CoV-2-Impfung mit BNT162b2
Six cases of pityriasis rosea following SARS-CoV-2 vaccination with BNT162b2
Outcomes of SARS-CoV-2 infection among children and young people with pre-existing rheumatic and musculoskeletal diseases
Increased prevalence of attention-deficit hyperactivity disorder symptomatology in patients with familial Mediterranean fever
Neurological and neurodevelopmental symptoms in children with familial Mediterranean fever and their siblings
Discontinuation of Colchicine Therapy in Children With Familial Mediterranean Fever
Minor Clinical Impact of COVID-19 Pandemic on Patients With Primary Immunodeficiency in Israel
Development of a New International Antiphospholipid Syndrome Classification Criteria Phase I/II Report: Generation and Reduction of Candidate Criteria
Hijab Pin Ingestions
OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death
Pyogenic sacroiliitis in children: don't forget the very young
Japanese scoring systems to predict resistance to intravenous immunoglobulin in Kawasaki disease were unreliable for Caucasian Israeli children
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies
A high and equal prevalence of the Q703K variant in NLRP3 patients with autoinflammatory symptoms and ethnically matched controls
Adenosine Deaminase 2 Deficiency: More Than Monogenic Vasculitis
High-dose aspirin for Kawasaki disease: outdated myth or effective aid?
Therapy with eculizumab for patients with CD59 p.Cys89Tyr mutation
Extending the Clinical Phenotype of Adenosine Deaminase 2 Deficiency
Familial Mediterranean fever
Update on Auto-Inflammatory Diseases and Familial Mediterranean Fever
Behçet's disease and cerebral sinus vein thrombosis in children: a case study and review of the literature
Sudden onset unexplained encephalopathy in infants: think of cannabis intoxication
Efficacy of Rituximab in Refractory Cold Agglutinin Hemolytic Anemia in a Patient with Ataxia-Telangiectasia
Rate and Clinical Presentation of Macrophage Activation Syndrome in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Canakinumab
Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib
Enteroviral Infection in a Patient with BLNK Adaptor Protein Deficiency
Seasonality of birth of patients with juvenile idiopathic arthritis
Iatrogenic Cushing Syndrome due to Intranasal Dexamethasone
Disturbed B and T cell homeostasis and neogenesis in patients with ataxia telangiectasia
Antiphospholipid antibodies in neonates with stroke--a unique entity or variant of antiphospholipid syndrome?
Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy
Diagnosis and classification of juvenile idiopathic arthritis
Diagnostic criteria of familial Mediterranean fever
Familial Mediterranean fever: a critical digest of the 2012-2013 literature
The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy
Pentraxin 3 is a marker of early joint inflammation in patients with juvenile idiopathic arthritis
Chronic chilblains: the clinical presentation and disease course in a large paediatric series
Dermatologic manifestations of ataxia-telangiectasia syndrome
Pharmacokinetics of colchicine in pediatric and adult patients with familial Mediterranean fever
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
FMF - clinical features, new treatments and the role of genetic modifiers: a critical digest of the 2010-2012 literature
Colchicine is a safe drug in children with familial Mediterranean fever
Novel immunotherapy for malignant melanoma with a monoclonal antibody that blocks CEACAM1 homophilic interactions
Cellular interactions of synovial fluid γδ T cells in juvenile idiopathic arthritis
NOD2/CARD15 gene mutations in patients with familial Mediterranean fever
Impact of persistent antiphospholipid antibodies on risk of incident symptomatic thromboembolism in children: a systematic review and meta-analysis
The relative contribution of environmental and genetic factors to phenotypic variation in familial Mediterranean fever (FMF)
T-cell compartment in synovial fluid of pediatric patients with JIA correlates with disease phenotype
Cellular and clinical report of new Griscelli syndrome type III cases
Children with oligoarticular juvenile idiopathic arthritis are at considerable risk for growth retardation
Neurologic presentation in children with ataxia-telangiectasia: is small head circumference a hallmark of the disease?
GammadeltaT cells in juvenile idiopathic arthritis: higher percentages of synovial Vdelta1+ and Vgamma9+ T cell subsets are associated with milder disease
The familial Mediterranean fever gene as a modifier of periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome
The feasibility and validity of forced spirometry in ataxia telangiectasia
Role of the R92Q TNFRSF1A mutation in patients with familial Mediterranean fever
EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: Final classification criteria
Familial Mediterranean Fever in the first two years of life: a unique phenotype of disease in evolution
Familial Mediterranean fever in children presenting with attacks of fever alone
Pregnancy outcomes in women with familial Mediterranean fever receiving colchicine: is amniocentesis justified?
TNF activates a NF-kappaB-regulated cellular program in human CD45RA- regulatory T cells that modulates their suppressive function
Reversible airway obstruction in children with ataxia telangiectasia
Familial Mediterranean fever in Ashkenazi Jews: the mild end of the clinical spectrum
Environmental factors and the geoepidemiology of juvenile idiopathic arthritis
Common infectious agents prevalence in antiphospholipid syndrome
Infectious antibodies in systemic lupus erythematosus patients
Is E148Q a benign polymorphism or a disease-causing mutation?
Exposure to Epstein-Barr virus infection is associated with mild systemic lupus erythematosus disease
The Ped-APS Registry: the antiphospholipid syndrome in childhood
Clinical disease among patients heterozygous for familial Mediterranean fever
MEFV mutation carriage in Israeli Jewish individuals from ethnicities with low risk for familial Mediterranean fever
Altered dendritic cells with tolerizing phenotype in patients with systemic lupus erythematosus
Pediatric antiphospholipid syndrome: clinical and immunologic features of 121 patients in an international registry
Intracardiac thrombus and pulmonary aneurysms in an adolescent with Behçet disease
Differentiation of post-streptococcal reactive arthritis from acute rheumatic fever
Periodic fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA syndrome) in adults
Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells
Neuropsychiatric lupus and infectious triggers
Acute otitis media in the first two months of life: characteristics and diagnostic difficulties
Pediatric antiphospholipid syndrome
The mosaic of autoimmunity: prediction, autoantibodies, and therapy in autoimmune diseases--2008
The mosaic of autoimmunity: hormonal and environmental factors involved in autoimmune diseases--2008
The mosaic of autoimmunity: genetic factors involved in autoimmune diseases--2008
Increased intracranial pressure related to systemic lupus erythematosus: a 26-year experience
Protracted febrile myalgia in children and young adults with familial Mediterranean fever: analysis of 15 patients and suggested criteria for working diagnosis
Pyrin and cryopyrin--similar domain sequence but opposite inflammatory consequence
Auto-inflammatory fever syndromes
2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis
A single testing of serum amyloid a levels as a tool for diagnosis and treatment dilemmas in familial Mediterranean fever
The incidence of giant cell arteritis in Jerusalem over a 25-year period: annual and seasonal fluctuations
Outcome of a national Israeli cohort of pediatric systemic lupus erythematosus
Peritoneal adhesions and intestinal obstructions in patients with familial Mediterranean fever--are they more frequent?
alpha1beta1 Integrin+ and regulatory Foxp3+ T cells constitute two functionally distinct human CD4+ T cell subsets oppositely modulated by TNFalpha blockade
Antiphospholipid syndrome and recurrent thrombosis in children
Use of complementary and alternative medicine among patients attending rheumatology clinics in Israel
Perceived efficacy among patients of various methods of complementary alternative medicine for rheumatologic diseases
Pemphigus following hepatitis B vaccination--coincidence or causality?
Autoimmune hepatitis: a part of the antiphospholipid syndrome?
Sludge ball, pseudolithiasis, cholelithiasis and choledocholithiasis from intrauterine life to 2 years: a 13-year follow-up
Heparin-induced recurrent anaphylaxis
The outcome of pregnancy in the wives of men with familial mediterranean fever treated with colchicine
Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene
Kingella kingae endocarditis and sepsis in an infant
Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis
Risk factors for cranial ischemic complications in giant cell arteritis
Increased morbidity and mortality in patients with antiphospholipid syndrome undergoing valve replacement surgery
Knowledge and expectations of patients receiving aeroallergen immunotherapy
Evaluation of adverse reactions to local anesthetics: experience with 236 patients
Intestinal protein loss and hypoalbuminemia in children with pneumonia
A man with swollen calf and discoloration of the foot
Evidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5A
Anti-IgE--a new treatment for allergic diseases
Hereditary angioedema first apparent in the ninth decade during treatment with ACE inhibitor
Leukotriene antagonists: additional treatment for chronic urticaria?
Successful treatment of delayed pressure urticaria with montelukast
Focal bacterial nephritis (lobar nephronia) in children
A new mutation in the CFTR gene, composed of two adjacent DNA alterations, is a common cause of cystic fibrosis among Georgian Jews
Urticaria in patients with hepatitis A virus infection
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Заболевания
Дефицит аденозиндезаминазы 2 (DADA2)
Семейная средиземноморская лихорадка
Болезнь Стилла
Лихорадка неясного генеза у детей
Наследственный ангионевротический отек
Процедуры
Терапия ингибиторами JAK
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