Дана Вольф

Должность: Вирусолог
Языки: Английский
Принимает: детей и взрослых

Профессор Дана Вольф - директор отделения клинической вирусологии

Образование

Ординатуру прошла на кафедре внутренних болезней университетской больницы Хадасса Эйн-Керем в Иерусалиме. Повышение квалификации в области вирусологии (цитомегаловирус), в Университете Калифорнии в Сан-Диего. Специализация по инфекционным заболеваниямв медицинском центре Хадасса.

С 1996 года - старший врач по инфекционным заболеваниям, а с 2001 года - директоро отделения клинической вирусологии  в больнице Хадасса. 

Профессиональная деятельность

Профессор Дана Вольф - врач-исследователь в области инфекционных заболеваний и директор отделения клинической вирусологии в медицинском центре Хадасса. Исследования проф. Вольф посвящены новым диагностическим и противовирусным стратегиям, с особым акцентом на цитомегаловирус - наиболее распространенную причину врожденных инфекций, а также на основные респираторные вирусы.

Проф. Вольф разработала уникальную систему ex vivo вирусной инфекции в нативных тканях-мишенях человека, раскрывающую способы передачи вируса и иммунной защиты в дыхательных путях человека и на границе между матерью и плодом. Полученные результаты привели к открытию новых пренатальных биомаркеров, которые предсказывают тяжесть врожденной цитомегаловирусной инфекции, и к разработке нового препарата против ЦМВ. Под ее руководством вирусологическая лаборатория Хадассы была признана одной из основных референсных лабораторий, аккредитованной по стандарту ISO 15189 и сотрудничающей с ВОЗ.

Проф. Вольф является членом нескольких национальных и международных консультативных комитетов, включая Израильский консультативный комитет по практике иммунизации и группу по подготовке к эпидемиям, а также исполнительный совет Европейского общества вирусологии.

Научные публикации

Factors Associated With the Ability of US Nursing Homes to Accept Residents With Severe Obesity
Implementation of pooled saliva tests for universal screening of cCMV infection
Decidual-tissue-resident memory T cells protect against nonprimary human cytomegalovirus infection at the maternal-fetal interface
Paying a Heavy Price: Costs of Care for People With Severe Obesity in Nursing Homes
Genome-wide loss-of-function screen using human pluripotent stem cells to study virus-host interactions for SARS-CoV-2
High rate of adenovirus detection in gastrointestinal biopsies of symptomatic stem cell transplant recipients
CLPTM1L is a GPI-anchoring pathway component targeted by HCMV
Intramuscular mRNA BNT162b2 vaccine against SARS-CoV-2 induces neutralizing salivary IgA
Boosting maternal and neonatal anti-SARS-CoV-2 humoral immunity using a third mRNA vaccine dose
SARS-CoV-2 Omicron Induces Enhanced Mucosal Interferon Response Compared to other Variants of Concern, Associated with Restricted Replication in Human Lung Tissues
Identification of SARS-CoV-2 Variants of Concern Using Amplicon Next-Generation Sequencing
Kinetics of Maternally Derived Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies in Infants in Relation to the Timing of Antenatal Vaccination
Maternal and Neonatal Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Neutralization After Antenatal Messenger RNA Vaccination
Amniotic fluid biomarkers predict the severity of congenital cytomegalovirus infection
Boosting maternal and neonatal humoral immunity following SARS-CoV-2 infection using a single messenger RNA vaccine dose
Severe Acute Respiratory Syndrome Coronavirus 2 Third Vaccine Immune Response in Multiple Sclerosis Patients Treated with Ocrelizumab
The Effect of Gestational Age at BNT162b2 mRNA Vaccination on Maternal and Neonatal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Levels
Response to tozinameran (BNT162b2) booster in twice-vaccinated kidney transplant and maintenance dialysis patients
Impact of tozinameran (BNT162b2) mRNA vaccine on kidney transplant and chronic dialysis patients: 3-5 months follow-up
Assessment of Response to a Third Dose of the SARS-CoV-2 BNT162b2 mRNA Vaccine in Patients With Solid Tumors Undergoing Active Treatment
External Quality Assessment of SARS-CoV-2 Sequencing: an ESGMD-SSM Pilot Trial across 15 European Laboratories
Timing of SARS-CoV-2 vaccination during the third trimester of pregnancy and transplacental antibody transfer: a prospective cohort study
Serologic response to COVID-19 infection and/or vaccine in cancer patients on active treatment
Humoral and T-Cell Response to SARS-CoV-2 Vaccination in Patients With Multiple Sclerosis Treated With Ocrelizumab
Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2
The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing
Human Nasal and Lung Tissues Infected Ex Vivo with SARS-CoV-2 Provide Insights into Differential Tissue-Specific and Virus-Specific Innate Immune Responses in the Upper and Lower Respiratory Tract
Neonatal SARS-CoV-2 Infections in Breastfeeding Mothers
Efficient Maternofetal Transplacental Transfer of Anti- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Antibodies After Antenatal SARS-CoV-2 BNT162b2 Messenger RNA Vaccination
Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests
Decreased prevalence rate of respiratory pathogens in hospitalized patients during the COVID-19 pandemic: possible role for public health containment measures?
Characteristics of Clinically Asymptomatic Patients with SARS-CoV-2 Infections, Case Series
Proactive screening approach for SARS-CoV-2 among healthcare workers
Human Nasal Turbinate Tissues in Organ Culture as a Model for Human Cytomegalovirus Infection at the Mucosal Entry Site
Large-scale implementation of pooled RNA extraction and RT-PCR for SARS-CoV-2 detection
Correction for Weisblum et al., "Zika Virus Infects Early- and Midgestation Human Maternal Decidual Tissues, Inducing Distinct Innate Tissue Responses in the Maternal-Fetal Interface"
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus
Measles-related hospitalizations and associated complications in Jerusalem, 2018-2019
Saliva Real-Time Polymerase Chain Reaction for Targeted Screening of Congenital Cytomegalovirus Infection
Digital PCR in bone marrow trephine biopsies is highly sensitive for MYD88L265P detection in lymphomas with plasmacytic/plasmacytoid differentiation
Intensive Care Admissions and Associated Severity of Influenza B Versus A During Influenza B Vaccine-mismatched Seasons
HPV genotype distribution among women with normal and abnormal cervical cytology presenting in a tertiary gynecology referral Clinic in Ethiopia
Evaluation of Nursing Facility Resident Safety During Implementation of the INTERACT Quality Improvement Program
The Human Cytomegalovirus Protein UL148A Downregulates the NK Cell-Activating Ligand MICA To Avoid NK Cell Attack
The Artemisinin Derivative Artemisone Is a Potent Inhibitor of Human Cytomegalovirus Replication
Diagnosis of HIV-1 infection: Performance of Xpert Qual and Geenius supplemental assays in fourth generation ELISA-reactive samples
APOBEC3A Is Upregulated by Human Cytomegalovirus (HCMV) in the Maternal-Fetal Interface, Acting as an Innate Anti-HCMV Effector
Zika Virus Escapes NK Cell Detection by Upregulating Major Histocompatibility Complex Class I Molecules
Diagnosis of Cytomegalovirus Infection during Exacerbation of Ulcerative Colitis
Barriers and Facilitators to Implementing a Change Initiative in Long-Term Care Using the INTERACT® Quality Improvement Program
Efficacy of inactivation of viral contaminants in hyperimmune horse plasma against botulinum toxin by low pH alone and combined with pepsin digestion
The expression level of C19MC miRNAs in early pregnancy and in response to viral infection
Letters
Analysis of Influenza and RSV dynamics in the community using a 'Local Transmission Zone' approach
Zika Virus Infects Early- and Midgestation Human Maternal Decidual Tissues, Inducing Distinct Innate Tissue Responses in the Maternal-Fetal Interface
HSV1 MicroRNA Modulation of GPI Anchoring and Downstream Immune Evasion
Hospital Transfers of Skilled Nursing Facility (SNF) Patients Within 48 Hours and 30 Days After SNF Admission
CEACAM1-Mediated Inhibition of Virus Production
HCMV vCXCL1 Binds Several Chemokine Receptors and Preferentially Attracts Neutrophils over NK Cells by Interacting with CXCR2
Lessons Learned From Root Cause Analyses of Transfers of Skilled Nursing Facility (SNF) Patients to Acute Hospitals: Transfers Rated as Preventable Versus Nonpreventable by SNF Staff
Root Cause Analyses of Transfers of Skilled Nursing Facility Patients to Acute Hospitals: Lessons Learned for Reducing Unnecessary Hospitalizations
Coxsackievirus A6 Polymorphic Exanthem in Israeli Children
Human cytomegalovirus induces a distinct innate immune response in the maternal-fetal interface
Transition toward Human Cytomegalovirus Susceptibility in Early Human Embryonic Stem Cell-Derived Neural Precursors
A heart breaking case of rapidly developing severe hemophagocytic syndrome secondary to chronic active EBV infection; a case report and review of the literature
Dynamic Co-evolution of Host and Pathogen: HCMV Downregulates the Prevalent Allele MICA∗008 to Escape Elimination by NK Cells
Models of vertical cytomegalovirus (CMV) transmission and pathogenesis
MicroRNA editing facilitates immune elimination of HCMV infected cells
Hematopoietic stem cell transplantation conditioning with use of rituximab in EBV related lymphoproliferative disorders
Coxsackievirus A6-related hand foot and mouth disease: skin manifestations in a cluster of adult patients
High rate of cytomegalovirus drug resistance among patients receiving preemptive antiviral treatment after haploidentical stem cell transplantation
Advances in immunotherapy of chronic myeloid leukemia CML
HSV-2 specifically down regulates HLA-C expression to render HSV-2-infected DCs susceptible to NK cell killing
Antiphospholipid antibodies during infectious mononucleosis and their long term clinical significance
Modeling of human cytomegalovirus maternal-fetal transmission in a novel decidual organ culture
Increased extent of and risk factors for pandemic (H1N1) 2009 and seasonal influenza among children, Israel
An outbreak of adenovirus type 7 in a residential facility for severely disabled children
Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation
Human cytomegalovirus UL97 kinase and nonkinase functions mediate viral cytoplasmic secondary envelopment
The humoral immune response of hematopoietic stem cell transplantation recipients to AS03-adjuvanted A/California/7/2009 (H1N1)v-like virus vaccine during the 2009 pandemic
Influenza A infection in young infants
The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination
Cytomegalovirus infection in pediatric rheumatic diseases: a review
Treatment of symptomatic congenital cytomegalovirus infection with intravenous ganciclovir followed by long-term oral valganciclovir
Association of human metapneumovirus with radiologically diagnosed community-acquired alveolar pneumonia in young children
Analysis of human cytomegalovirus-encoded microRNA activity during infection
Epstein-barr virus-related diarrhea or exacerbation of inflammatory bowel disease: diagnostic dilemma
Emergence of oseltamivir-resistant influenza A/H3N2 virus with altered hemagglutination pattern in a hematopoietic stem cell transplant recipient
The antiviral activities of artemisinin and artesunate
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation
The clinical spectrum of cytomegalovirus colitis in adults
Steroids for deteriorating herpes simplex virus encephalitis
Clinical inquiries. Should we use SSRIs to treat adolescents with depression?
Severe Epstein-Barr virus-associated hemophagocytic syndrome in six adult patients
Host immune system gene targeting by a viral miRNA
Simkania negevensis in bronchoalveolar lavage of lung transplant recipients: a possible association with acute rejection
Enterovirus, cytomegalovirus, and Epstein-Barr virus infection screening in idiopathic sudden sensorineural hearing loss
NK cytotoxicity mediated by CD16 but not by NKp30 is functional in Griscelli syndrome
Clinical inquiries. What predicts a successful smoking cessation attempt?
Structural changes in human cytomegalovirus cytoplasmic assembly sites in the absence of UL97 kinase activity
Hyponatremia associated with adenovirus infection in twin infants
Comparison of human metapneumovirus, respiratory syncytial virus and influenza A virus lower respiratory tract infections in hospitalized young children
Kaposi's sarcoma-associated herpesvirus: clinical, diagnostic, and epidemiological aspects
Varicella zoster virus encephalitis in a previously healthy five-year-old child with herpes zoster ophthalmicus
Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus
Early-onset Guillain-Barré syndrome associated with reactivation of Epstein-Barr virus infection after nonmyeloablative stem cell transplantation
A summer outbreak of influenza A virus infection among young children
Osteomyelitis of the pubis after strenuous exercise. A case report and review of the literature
Tongue necrosis and pericarditis
High seroprevalence of human metapneumovirus among young children in Israel
Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors
Multidrug-resistant Trichosporon asahii isolates are susceptible to voriconazole
Emergence of late cytomegalovirus central nervous system disease in hematopoietic stem cell transplant recipients
Hospital librarianship in the United States: at the crossroads
Multidrug-resistant Trichosporon asahii infection of nongranulocytopenic patients in three intensive care units
Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial
Indolent aspergillus arthritis complicating fludarabine-based non-myeloablative stem cell transplantation
Detection of human herpesvirus-8 DNA in kidney allografts prior to the development of Kaposi's sarcoma
Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsidation
Emergence of multiple human cytomegalovirus ganciclovir-resistant mutants with deletions and substitutions within the UL97 gene in a patient with severe combined immunodeficiency
High rate of candidemia in patients sustaining injuries in a bomb blast at a marketplace: a possible environmental source
Early emergence of ganciclovir-resistant human cytomegalovirus strains in children with primary combined immunodeficiency
Characterization of the human cytomegalovirus UL97 gene product as a virion-associated protein kinase
Thoracic aorta transobturator bipopliteal bypass as eventual durable reconstruction after removal of an infected aortofemoral graft
Digoxin intoxication in a patient with end-stage renal disease: efficacy of digoxin-specific Fab antibody fragments and peritoneal dialysis
Candida abscess of the thyroid in a patient with acute lymphocytic leukemia
Detection of human cytomegalovirus mutations associated with ganciclovir resistance in cerebrospinal fluid of AIDS patients with central nervous system disease
Infection of a ruptured aortic aneurysm and an aortic graft with bacille Calmette-Guérin after intravesical administration for bladder cancer
Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma
Early diagnosis of human cytomegalovirus disease in transplant recipients by DNA amplification in plasma
Pathophysiology and treatment of clinically resistant cytomegalovirus retinitis
Diagnosis of human cytomegalovirus central nervous system disease in AIDS patients by DNA amplification from cerebrospinal fluid
Rabbits fed on beta-carotene have higher serum levels of all-trans retinoic acid than those receiving no beta-carotene
Searching for information about audiovisuals in a hospital library
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